“Self-checkout is a good example of the difficulty of defining the “success” or “failure” of a technology without specifying for whom.”

This treatment itself is kind of a dead end, because as you say, it cannot be scaled up to treat millions of people. But, it could be used to treat a few extremely wealthy people with HIV, every year. Where there is hope, is that one day, a virus might be used as a vector, to carry a similar gene into the bone marrow…

Is mystery meat a topping at either store?

It’s a mistake to require other antidepressants to be used first, because they take weeks to be effective whereas ketamine and related drugs work in one day to relieve depression.  Clinical Depression is not merely being sad, it is causing brain damage and should be stopped as quickly as possible.

What is happening is that ketamine like drugs are potentially an entire class of drugs that work with glutamate instead of serotonin.  J&J is not the only company working on these.  And side effects are critical, because they can only ethically administer old fashioned ecstasy in a clinical setting, but some of the…

The prospect of Ilhan Omar leading/dragging a reluctant Dem leadership into an impeachment process, during an election year, might not be as bad for Republicans as you think.

The guy was late for a train.

Large Turbodiesel pickups get heavily discounted after 200,000 and yet, even if they are not meticulously maintained, may still have a great deal of life in them.

The choice of a barcode, is partly so that there is still touchscreen entry of the voter’s choices as they make them, and then a form of record that allows no partially filled boxes or spots, no hand written “X” which can be confused as a crossed out vote, and no double votes, to be second guessed. There is no…

A barcode would make it easy for a machine to read large numbers of paper ballots, whereas machine reading hand written ballot is more difficult. When you pass through your gate at the airport, do you confront the gate attendant and accuse her of trying to cheat you, because she scans your boarding pass?  If the state…

I saw a boxing match featuring teen girl fighters at a nightclub once.  It was meant to be titillating.

Did they get a Papa John’s, instead?

Do they cater weddings?

I remember when Health Departments all over America were advised to ban wooden cutting boards in Foodservice and use instead, plastic polycarbonate ones, then only available in white.  We were told that the plastic cutting boards harbored less bacteria and were more sanitary.  My local health district told me I had to…

It will be fascinating to watch the damage that American crewed capsules do to the Russian space program. Right now, America and Europe largely subsidize the inefficient Russian manned space program. A total collapse of Russian access to space could follow, as economy of scale falls and yet more skilled engineers try…

Dems are willing to excuse every stupid thing AOC says, but when it is about another dem who is a sacred cow, then her low wattage is more difficult to ignore.

For decades, polls show that the public has an extremely low opinion of Congress.  However, constituents usually have a better opinion of their own district’s elected representatives.  They may want new blood, but they love good ole’ Joe Biden, specifically.  Even Republicans like me have relatively warm feelings…

The older they are, the higher they are polling right now.  That means voters might want young blood in theory, but tell pollsters another story when confronted with the individual candidates.

Wouldn’t they have to pay you to live in Mississippi?

When will McDonalds issue a plus sized, clothing line? I understand McDonalds’ socks run right out the door.