There are studies about mast cell activity and IC. My estrogen was fluctuating wildly last year. I had a couple allergy attacks (which is very rare for me) because estrogen triggers mast cells. I’m convinced this is partly why I was susceptible. First I had low estrogen, thinning my tissues. Then I over dosed on…

I got a burner account just to reply to you. Are you sure it’s not urethritis or IC (interstitial cystitis, which is basically chronic urethritis)? They are VERY often misdiagnosed as UTIs and antibiotics do NOTHING for them. If you have IC, take Prelief tablets to alkalize your urine. Then eliminate all acid-y foods…