I'm with you there, thank goodness our governments and corporations keep the rich in check and don't allow them to cheat or bully us.

The mice don't have Alzheimer's, which is a human disease. Instead, mouse models aim to reproduce what we know about the disease and its progression in people. This would include the amyloid-beta plaques that are characteristic of AD, molecular markers of AD progression, as well as behavior in cognitive ability tests,…

This was a very strong study in animal models that will hopefully translate to success in human patients. Reasons to be hopeful 1, 2, 3;

What you say certainly puts this into sharp perspective. You have clearly encountered real tragedy of a kind that at least I have never had to. I do understand the anger and I actually regret leaving that comment - its more judgemental than I'd like to be.

I completely agree with you on every point you make and wish that my comment had been similarly thought through. In fact it was made in reaction to reading some of the more extreme comments posted here. Frankly, I immediately regretted the knee-jerk reaction and went back to delete the comment - seems I can't even do…

Its absolutely tragic that something so old should be destroyed so pointlessly, but I don't see why the nature of its pointless destruction should have such special significance. I knew I shouldn't have read through the comments, but it seems that for some of the more vigilante-minded around here the tragedy is that…

You beat me to it. It sounds kinda similar, doesn't it?

Pixellated. Some times welcome, some times not so much.

I stand corrected, and somewhat chastened (I should know better, having read "what the hell have those cancer researchers been doing" many times before). What you say, of course, makes a lot of sense (though its been a while since I did undergrad immunology), and I can see how it is not going to be easy to get an…

I tried to persuade my wife to watch it for exactly that reason - sadly she wouldn't watch it.

Rather than sounding counter-intuitive, doesn't this approach sound completely and utterly intuitive, to the point where you have to wonder, if this is a new approach what have the vaccine researchers been doing up til now?

I'm enjoying it - at times its easy to get distracted and start thinking about who's holding the camera, but for the most part it manages to keep me in the situation - one of the fastest hours on TV.

I actually thought the Once Upon A Time synopsis was a joke set-up, was waiting for the punch line. Slightly disappointed. Hoping that Awake will not disappoint though.

Spoiler notifications for the Twilight Zone needed?

Thanks. I should most probably have reasoned that.

I actually kind of like that idea (about Olivia's "death"). Especially since much of what September says is not quite as it initially seems - "you must go home, Peter", for instance. And it would make for a much happier ending - but then, I'm not thinking about endings, happy or otherwise.

Yes, I thought Lincoln was acting like a total dick - especially after his star turn as Walter's tough cop partner the week before.

Trying very hard not to think about how Fringe will end.

I'm well aware that most cancer drugs don't make it into the clinic, but all successful clinical development programs are driven by preclinical research. Someone has to get excited about it or it won't happen. In this case the approach is perfectly sound - targeting pathways upstream of Akt in a tissue-specific manner…

Sometimes I worry that my brain is going to empty and I'm going to start reliving my childhood.