I'm really enjoying this show, but I can't help wondering how they're going to consistently integrate the gathering swarm of adversaries - Elias, Root, bent cops and dodgy CIA suits - into the storyline. Will they form a villainous coalition, a dark league of cruel injustice to thwart the efforts of our heroes Reese,…

I get the William Golding reference - any chance you could tell me who Emperor Titus was, without me googling him?

This is NOT "pseudoscience". The experiments performed in the study are entirely appropriate, and their conclusions reasonable. The role that GC-C and cGMP play in downregulating Akt obviously infer a potential connection to cancer, as well as inflammatory diseases. Its not clear to me why you would want to reserve…

Yikes, not sure if I'm emotionally prepared for this episode! And people in a different timeline, i.e. on the East coast, have already started watching it!

There are at least 3 GC-C agonists in clinical development for constipation - they're well tolerated and have few side effects. So if the animal studies hold up, having a drug with a proven safety record might be a promising approach to cancers or inflammatory diseases of the gut.

Differences between Battle Royale novel and movie, at least as I remember;

That was one of most wonderfully evocative pieces about quantum shenanigans I've read in quite a while. I have an image of a neutron smoking a cigarette now.

I understand, and its great that you cited the work from Janda's lab. But it seems that even Janda doesn't really have a good handle on the shortcomings of the Mexican animal studies - until they're published noone will. Like I say, I don't like to overly criticize (there are plenty of others around here to do that).

If you're suggesting that drug suppliers will find another opioid not recognized by the anti-heroin vaccine to sell to addicts, thats probably true - sooner or later they'd probably start engineering heroin to evade immune detection.

I don't like to unecessarily criticise science posts here, because they're generally very good, but The Daily Mail is not what I'd call a credible source of research news - its not even a credible source of news in general. Nor are any of the sources cited in the tabloid's article. Why not write a post led by the…

"You ever see two cats in a bag?" says Reese to a couple of bad guys in the trunk of his car.

Cute theory. Even cuter adjective describing it. I'd use it on a daily basis if it weren't bound to sound atrocious.

But are we sure of cause and effect here? I'd argue that success in sports, especially rugby, may lead to behavior and lifestyles conducive to weight gain; more celebratory pints, fewer training sessions, more celebratory pints, fewer worries and more celebratory pints.

Great idea, duly bookmarked. Interesting looking editorial board - glad to see Sean Carroll on it, and Annalee of course.

Alcatraz - not so much "covered in breadcrumbs" as lightly dusted with confectioner's sugar.

#2 for The Walking Dead definitely - in fact, I see no reason to wait until the end.

I'd very much like to see a transatlantic science elucidation smackdown between Brian Cox and Neil deGrasse Tyson, two of the truly great communicators of science from either side of the ocean.

"I've been accepted at Law School."

Not pretending to really understand this, but how would spontaneous time crystallization happen - don't spatial crystals require some kind of seeding? And doesn't it all run kind of counter to the second law? Like I say, not that I can claim to really have much understanding of this.

I finally figured out why I keep watching this show and its Bear McCreary's musical score. I can't keep watching it hoping for it to fulfill its promise, because it isn't going to. The main problem I have is that I simply don't care at all about a single character on the show. I used to like Glenn, but he's gone all…