He may be alluding to the fact that Tim Allen, before his acting career, was a cocaine dealer who did federal prison time.
"On October 2, 1978, Allen was arrested in the Kalamazoo/Battle Creek International Airport for possession of over 650 grams of cocaine. He subsequently pleaded guilty to drug trafficking charges…

Not having realistic bodies is pretty much the entire point of cartoons, is it not? And what of the stick figures in XKCD and Cyanide & Happiness? I'm honestly unsure if this is activism or parody; Poe's Law in effect.