A non-Skrull alternate universe version of him was the main villain in The Thanos Imperative a few years ago. He came from the Cancerverse and still fought Thanos. And then he died. Bad luck for Mar-Vell.

You're thinking of Lady Octopus, Carolyn Trainer, who was originally Doctor Octopus after the real Doctor Octopus was killed by Spider-Man's crazy clone, Kaine, and changed her name when Otto came back out of respect. Her robot arms actually had several improvements over Otto's, including a force field, anti-web…

2-Do 2-List