The Holy Grail of diet drugs would be something that resets your body’s “set point” weight at a desired level, at which point your metabolism would just rev up whenever you eat more than usual rather than you gaining weight.

For non-diabetic people when the drug is prescribed in heavy doses it’s just an appetite suppressant. This result is entirely unsurprising. Stop the drug, go back to binge eating.

And even bariatric surgery has mixed results long-term. Within ten years, 25% of bariatric surgery patients regain all the weight they initially lost. Moreover, 20% of patients fail to achieve “significant weight loss” (quantified as loss of more than 50% of bodyweight) after bariatric surgery.

I feel like I might come across as an asshole about this, this is also what happens when you come off a super restrictive diet and fall back into previous eating habits. I guess my question is, did she change her eating habits while she was on the drug, and then not stick with it once she stopped taking it, or is…

Everyone in my family is short. My brother (5'6", in his 40s at the time) said to me after his divorce that he was astonished to find that women didn’t really care about his height. He said the two things women talked about wanting from men were kindness and a sense of humor. I pointed out that I could have told him…

He’s an incel. He can’t stand the fact that women have different thoughts and opinions than him and his empirical evidence that he’s collected through self-pity.

You lack the emotional intelligence to participate in this conversation. As well as the intellectual ability.

You could have 100 women write down 10 things they are looking for from their ideal partner, compile that data and create a list of 10 or 12 things that women are looking for, become the ideal embodiment of those things, make it your life’s work to make sure that you have those 10 or 12 characteristics, and you can…

The reason you’re sorting through 100's of pages is because Etsy is allowing 3rd party resellers and drop shippers (people who you buy a product from, then they go to AliBaba, order and then put your address as the delivery address) to operate, despite these shops not being permitted according to Etsy’s own…

I had friends who were alcoholics that treated St.Patrick’s like a sacred holiday. I still drink a little now and then but can’t stand people who live for shit like that. One of those alcoholics went sober but there are plenty more that treat binge drinking like a badge of honor. The facebook memes about this shit are…

Because it’s disgusting to talk about a war like it’s a reality show, focusing not on this man’s bravery, but on his looks.   

I won’t address the part that StefanJammers did, because they did a good job there. But what I will say about “makeup or tutus or unicorns” is that that’s what kids use to signify gender and sex when they’re very young. What research has been done shows that gender identity usually solidifies in the first few years of…

I mean, I care about folks dehumanizing women by intentionally making them look a way society places inherent lesser value on. It’s playing into sexist bullshit tropes that a woman is less worth of care, compassion, and human dignity if she’s less attractive.

And today’s winner of Pin the Tail on the Biphobia is: whyamihereidk! 

It feels to me like the author was maybe a bit ashamed to be in a relationship with a cishet man, and didn’t want to be judged as not being queer enough. There are a lot of queer/bi/pan women that get a lot of crap for being in a “straight” relationship.

One of your links is the US attorney who gave him a plea-deal claiming “I was told he belonged to intelligence” because said attorney wanted a role in the US Cabinet. Wow, what a trustworthy credible source that is...

Nothing like antisemitic tropes getting brought in to this.

Often those that are attracted to children are victims of abuse. I read an account of a man that went through abuse as a child and never had a relationship as an adult because he was attracted to children and didn’t want to risk having his own kids. He was able to find a sympathetic psychologist and get help. I feel…

“I don’t think it should be a struggle not to drink. We should help the victims of drunk drivers instead.”