You need to learn to put things in context. The purpose of the second amendment was to make sure the individual citizens could protect themselves against a possibly corrupt government. Nowadays, people buy guns to shoot the person robbing them (or worse, to shoot innocent people). That is NOT what the second amendment…

"Such as?" Seriously? Have you ever WATCHED Bill O'Reilly? He's the worst troll in the history of television. If you watch two or three episodes of his show and can't find anything he says completely idiotic, I fear for your mind.

No one is saying "if you have a gun, you're going to kill someone every day". We're just saying "if you have a gun, you have it to use as an attack weapon".

I see no one here makes generalizations, polarizations, or just plain ignorant remarks...

Yes, I am. When a dog gets a surgery, we put a cone on their heads for awhile. Why? To look good? No, it's to stop them from biting their stitches and hurting themselves. We put up fences to keep animals away from dangerous places, i.e. busy roads, so they don't hurt themselves. Etc.

...yes, yes it is. The chemicals binding to receptors in the brain are what create the addiction. Blocking those receptors from being activated interferes with the addiction.

It wasn't nonsense. I wasn't at all claiming you'd definitely be addicted to morphine if you have it. I was saying it's possible and it happens, whereas blocking that dopamine rush makes it much LESS likely and, if done efficiently enough, perhaps impossible.

An antagonist doesn't strip anything away, it fits into the receptor and blocks other chemicals from doing so. Naloxone, as an antagonist, simply fits into the TLR4 receptor and blocks it from being activated by other chemicals (i.e. opioids). The TLR4 is what triggers the release of dopamine, i.e. the high. And no,…

No one says it's just feeling good, and no one said that something addictive will make everyone addicted always. But the dopamine rush, which creates the high, is a requirement for addiction in most cases. It's what's known as required but not sufficient. I.E. you need to drink alcohol to get drunk, but drinking…

I can't find any sources that say that, though admittedly I just did a very cursory search. Mind backing that up with reliable sources?

Ah. Cool. I've never heard of it before. I wonder if the Twitter guys are taking inspiration from this?

No. In other words, we already started with opium, so at least now we have an end to the chain.

Of course not, you need psychotherapy as well. But you do still need both a psychological treatment as well as a physical one. This seems like a great step forward in treating the physical half.

...yes. Chemicals cause the addiction. Using chemicals to interfere with those opioids interferes with the addiction.

They could try, but they'd no longer ever get the high no matter how much they increase. So the rehab center giving them the treatment could let them try as much as they want, and if they overdose they're in a place equipped to keep them safe. At that point, they'd know they can't get high anymore.

And let's be honest here...we now know the exact receptors these drugs work on and how they do what they do, etc. We didn't before. The more you know, the better you can predict the effects. I'm not saying we're infallible, just that we're more likely to understand the addictiveness of a drug if we know how it works.

I suppose anyone who blogs and wants a more well-rounded blogging platform? I don't know. It needs more work at the moment before I can figure it all out.

And then...addiction. Two sides of the coin.

Because it's a minor constituent of Suboxone. The main ingredient there is the buprenorphine. It's like claiming that drinking a solution of 4 parts salt and 1 part water would have the same effect as drinking pure water. Obviously, they're two very different things, even though one contains the other.

Exactly. The buprenorphine is the main constituent of Suboxone (4:1 is quite a ratio). It's what makes it Suboxone. It's what acts on the other receptors. That's the difference between the two. It's like the difference between a solution of 4 parts salt to 1 part water and just pure water.