It's a good thing you're so good at judging a joke you've never seen instead of just looking it up. The sister is totally fine with getting raped and is all "ooh youuuu" because they play playful pranks on eachother all the time. The sister isn't the butt of the joke, it's the fact that they treat rape as just another…

"I'm not condoning rape, obviously—you should never rape anyone. Unless you have a reason, like if you want to fuck somebody and they won't let you." How is this not using the act of rape as the punchline? It's more about the rapists mentality than the victims, but it's still about rape being absurdly casually…

So the initial rape joke that the heckler was objecting to loudly was fine, but Tosh's turning the joke onto the heckler was what crossed the line? I don't think a comedian has any obligation to make a disruptive member of his audience feel comfortable; in fact I think the "successful" way to deal with a heckler is to…

You seem to have forgotten that Tosh's feedback was positive from the people who were in attendance (that's what particularly seemed to upset the heckler, the entire audience laughed). He was interrupted, and insulted his heckler successfully making the audience laugh and the heckler leave, so his feedback WAS…